ALDH1A2 Rabbit Polyclonal Antibody (CAB7503)
- SKU:
- CAB7503
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | ALDH1A2 Rabbit Polyclonal Antibody |
SKU: | CAB7503 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human ALDH1A2 (NP_733797.1). |
Sequence: | MTSS KIEM PGEV KADP AALM ASLH LLPS PTPN LEIK YTKI FINN EWQN SESG RVFP VYNP ATGE QVCE VQEA DKAD IDKA VQAA RLAF SLGS VWRR MDAS ERGR LLDK LADL VERD RAVL ATME SLNG GKPF LQAF YVDL QGVI KTFR YYAG WADK IHGM TIPV DGDY FTFT RHEP IGVC |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | DIH4; RALDH2; RALDH2-T; RALDH(II); ALDH1A2 |
Positive Sample: | SW620,293T,Mouse liver,Mouse kidney,Mouse testis,Mouse lung,Rat liver |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm. |
Calculated MW: | 57kDa |
Observed MW: | 57kDa |
This protein belongs to the aldehyde dehydrogenase family of proteins. The product of this gene is an enzyme that catalyzes the synthesis of retinoic acid (RA) from retinaldehyde. Retinoic acid, the active derivative of vitamin A (retinol), is a hormonal signaling molecule that functions in developing and adult tissues. The studies of a similar mouse gene suggest that this enzyme and the cytochrome CYP26A1, concurrently establish local embryonic retinoic acid levels which facilitate posterior organ development and prevent spina bifida. Four transcript variants encoding distinct isoforms have been identified for this gene.
Purification Method: | Affinity purification |
Gene ID: | 8854 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |