ALDH1A1 Rabbit Polyclonal Antibody (CAB1802)
- SKU:
- CAB1802
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
| Product Name: | ALDH1A1 Rabbit Polyclonal Antibody |
| SKU: | CAB1802 |
| Size: | 20uL, 100uL |
| Isotype: | IgG |
| Host Species: | Rabbit |
| Reactivity: | Human,Mouse,Rat |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 301-400 of human ALDH1A1 (NP_000680.2). |
| Sequence: | QCCI AASR IFVE ESIY DEFV RRSV ERAK KYIL GNPL TPGV TQGP QIDK EQYD KILD LIES GKKE GAKL ECGG GPWG NKGY FVQP TVFS NVTD EMRI AKEE |
| Tested Applications: | WB IHC-P IF/ICC ELISA |
| Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
| Synonyms: | ALDC; ALDH1; HEL-9; HEL12; PUMB1; ALDH11; RALDH1; ALDH-E1; HEL-S-53e; ALDH1A1 |
| Positive Sample: | HepG2,A-549,K-562,Mouse lung,Mouse liver,Mouse testis,Rat lung,Rat kidney |
| Conjugate: | Unconjugated |
| Cellular Localization: | Cytoplasm. |
| Calculated MW: | 55kDa |
| Observed MW: | 55kDa |
The protein encoded by this gene belongs to the aldehyde dehydrogenase family. Aldehyde dehydrogenase is the next enzyme after alcohol dehydrogenase in the major pathway of alcohol metabolism. There are two major aldehyde dehydrogenase isozymes in the liver, cytosolic and mitochondrial, which are encoded by distinct genes, and can be distinguished by their electrophoretic mobility, kinetic properties, and subcellular localization. This gene encodes the cytosolic isozyme. Studies in mice show that through its role in retinol metabolism, this gene may also be involved in the regulation of the metabolic responses to high-fat diet.
| Purification Method: | Affinity purification |
| Gene ID: | 216 |
| Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |
 | Western blot analysis of various lysates using ALDH1A1 Rabbit pAb (CAB1802) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s. |
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