The ALDH1A1 Polyclonal Antibody (CAB1802) is a powerful tool for researchers studying ALDH1A1, an enzyme involved in cellular metabolism and stem cell differentiation. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the ALDH1A1 protein, this antibody enables precise detection and analysis in a variety of cell types, making it an essential tool for investigations in stem cell biology, cancer research, and drug development.ALDH1A1, also known as aldehyde dehydrogenase 1 family member A1, plays a crucial role in maintaining cellular homeostasis and differentiation processes.
Its dysregulation has been implicated in various diseases, including cancer and developmental disorders. By studying the function of ALDH1A1, researchers can gain valuable insights into disease mechanisms and potentially identify new therapeutic targets for treatment.With its high specificity and reliability, the ALDH1A1 Polyclonal Antibody (CAB1802) is a valuable asset for any research laboratory looking to delve into the complex world of cellular metabolism and stem cell biology. Its versatility and accuracy make it an indispensable tool for researchers seeking to unravel the mysteries of ALDH1A1 and its implications in health and disease.
Product Name:
ALDH1A1 Rabbit Polyclonal Antibody
SKU:
CAB1802
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 301-400 of human ALDH1A1 (NP_000680.2).
The protein encoded by this gene belongs to the aldehyde dehydrogenase family. Aldehyde dehydrogenase is the next enzyme after alcohol dehydrogenase in the major pathway of alcohol metabolism. There are two major aldehyde dehydrogenase isozymes in the liver, cytosolic and mitochondrial, which are encoded by distinct genes, and can be distinguished by their electrophoretic mobility, kinetic properties, and subcellular localization. This gene encodes the cytosolic isozyme. Studies in mice show that through its role in retinol metabolism, this gene may also be involved in the regulation of the metabolic responses to high-fat diet.
Purification Method:
Affinity purification
Gene ID:
216
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates using ALDH1A1 Rabbit pAb (CAB1802) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
