Aldh1a1 Antibody (PACO24864)
- SKU:
- PACO24864
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
Aldh1a1 Antibody (PACO24864)
The ALDH1A1 Polyclonal Antibody (PACO24864) is a valuable tool for researchers studying ALDH1A1, an important enzyme involved in the oxidation of intracellular aldehydes. This antibody is raised in rabbits and is highly reactive with human samples, making it ideal for use in Western blot applications. By specifically binding to the ALDH1A1 protein, researchers can accurately detect and analyze its expression in various cell types.ALDH1A1 is known for its role in retinoic acid biosynthesis and its involvement in processes such as stem cell differentiation, cell proliferation, and drug resistance.
Its dysregulation has been implicated in various diseases, including cancer, neurodegenerative disorders, and metabolic diseases. By studying ALDH1A1 using this antibody, researchers can gain valuable insights into its function and potential therapeutic implications in these disease contexts.Overall, the ALDH1A1 Polyclonal Antibody (PACO24864) is a reliable tool for researchers seeking to explore the role of ALDH1A1 in cellular processes and disease pathogenesis. Its high reactivity and specificity make it a valuable asset for studies in oncology, stem cell biology, and drug development.
| Antibody Name: | Aldh1a1 Antibody (PACO24864) |
| Antibody SKU: | PACO24864 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:2000 |
| Species Reactivity: | Mouse |
| Immunogen: | Recombinant Mouse Retinal dehydrogenase 1 protein (2-501AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot All lanes: Aldh1a1 antibody at 8µg/ml + Mouse eye tissue Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 55 kDa Observed band size: 55 kDa . |
| Background: | In addition to the activity on acetaldehyde and related substrates, is also involved in the oxidation of aldehydes derived from biogenic amines such as epinephrine and norepinephrine, as well as the aldehydes generated via lipid peroxidation. Binds free retinal and cellular retinol-binding protein-bound retinal. Can convert/oxidize retinaldehyde to retinoic acid, (By similarity). |
| Synonyms: | Retinal dehydrogenase 1 (RALDH 1) (RalDH1) (EC 1.2.1.-) (EC 1.2.1.36) (ALDH-E1) (ALHDII) (Aldehyde dehydrogenase family 1 member A1) (Aldehyde dehydrogenase, cytosolic), Aldh1a1, Ahd-2 Ahd2 Aldh1 |
| UniProt Protein Function: | Can convert/oxidize retinaldehyde to retinoic acid. Binds free retinal and cellular retinol-binding protein-bound retinal (). May have a broader specificity and oxidize other aldehydes in vivo (). |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | P24549 |
| NCBI GenInfo Identifier: | 85861182 |
| NCBI Gene ID: | 11668 |
| NCBI Accession: | NP_038495.2 |
| UniProt Secondary Accession: | P24549,Q7TQJ0, Q811J0 |
| UniProt Related Accession: | P24549 |
| Molecular Weight: | 56.3 kDa |
| NCBI Full Name: | retinal dehydrogenase 1 |
| NCBI Synonym Full Names: | aldehyde dehydrogenase family 1, subfamily A1 |
| NCBI Official Symbol: | Aldh1a1Â Â |
| NCBI Official Synonym Symbols: | E1; Ahd2; Ahd-2; Aldh1; Raldh1; Aldh1a2Â Â |
| NCBI Protein Information: | retinal dehydrogenase 1 |
| UniProt Protein Name: | Retinal dehydrogenase 1 |
| UniProt Synonym Protein Names: | ALDH-E1; ALHDII; Aldehyde dehydrogenase family 1 member A1 |
| Protein Family: | Retinal dehydrogenase |
| UniProt Gene Name: | Aldh1a1Â Â |
| UniProt Entry Name: |
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