The ALDH1A1 Rabbit Monoclonal Antibody is a powerful tool for researchers investigating ALDH1A1, an important enzyme involved in cellular metabolism and stem cell differentiation. This antibody, produced using rabbit monoclonal technology, exhibits high specificity and sensitivity for detecting ALDH1A1 in human samples, making it ideal for use in Western blot and immunohistochemistry applications.ALDH1A1, a member of the aldehyde dehydrogenase family, plays a key role in retinoic acid biosynthesis and is known to be a marker for cancer stem cells in various types of tumors.
By targeting ALDH1A1, researchers can gain insights into the biology of cancer stem cells and potentially develop new therapeutic strategies for cancer treatment.This antibody binds specifically to the ALDH1A1 protein, allowing for precise detection and quantification in experimental samples. Its reliability and performance make it a valuable tool for studies in cancer biology, stem cell research, and drug discovery. Researchers can trust the ALDH1A1 Rabbit Monoclonal Antibody to deliver accurate and reproducible results in their investigations.
Product Name:
ALDH1A1 Rabbit Monoclonal Antibody
SKU:
CAB0157
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 250-350 of human ALDH1A1 (NP_000680.2).
The protein encoded by this gene belongs to the aldehyde dehydrogenase family. Aldehyde dehydrogenase is the next enzyme after alcohol dehydrogenase in the major pathway of alcohol metabolism. There are two major aldehyde dehydrogenase isozymes in the liver, cytosolic and mitochondrial, which are encoded by distinct genes, and can be distinguished by their electrophoretic mobility, kinetic properties, and subcellular localization. This gene encodes the cytosolic isozyme. Studies in mice show that through its role in retinol metabolism, this gene may also be involved in the regulation of the metabolic responses to high-fat diet.
Purification Method:
Affinity purification
Gene ID:
216
Clone Number:
ARC52440
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates, using ALDH1A1 Rabbit mAb (CAB0157) at 1:20000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.