The Aldehyde Oxidase Polyclonal Antibody (CAB3586) is a valuable tool for researchers studying aldehyde oxidase, an enzyme involved in the metabolism of various drugs and toxins in the liver. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications.Aldehyde oxidase plays a crucial role in drug metabolism and detoxification processes, making it a key target for pharmacological studies. By specifically binding to the aldehyde oxidase protein, this antibody enables researchers to detect and analyze its expression in different cell types and tissues, facilitating investigations into drug interactions, toxicity, and efficacy.
Understanding the function and regulation of aldehyde oxidase is essential for developing safe and effective therapeutic interventions, as alterations in its activity can impact drug metabolism and lead to adverse reactions. By utilizing the Aldehyde Oxidase Polyclonal Antibody (CAB3586), researchers can further explore the role of this enzyme in drug biotransformation and its implications for personalized medicine and drug development.
Product Name:
AOX1 Rabbit Polyclonal Antibody
SKU:
CAB3586
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 340-590 of human AOX1 (NP_001150.3).
Aldehyde oxidase produces hydrogen peroxide and, under certain conditions, can catalyze the formation of superoxide. Aldehyde oxidase is a candidate gene for amyotrophic lateral sclerosis.
Purification Method:
Affinity purification
Gene ID:
316
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using AOX1 antibody (CAB3586) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
