The ALBA Polyclonal Antibody (PAC050846) is a valuable tool for researchers studying the ALBA protein, a key player in DNA packaging and repair processes. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By targeting the ALBA protein, this antibody enables precise detection and analysis in a variety of cell types, making it an essential component for studies in molecular biology and genetics.
ALBA, also known as a chromatin-binding protein, is instrumental in maintaining genome stability and regulating gene expression. Its involvement in DNA repair and chromosome organization highlights its significance in cellular processes, making it a promising target for research into genetic disorders, cancer, and developmental biology. Understanding the function of ALBA is critical for advancing knowledge in these areas and potentially uncovering new therapeutic strategies.
Antibody Name:
albA Antibody (PACO50846)
Antibody SKU:
PACO50846
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:500-1:5000
Species Reactivity:
Pyrococcus furiosus
Immunogen:
Recombinant Pyrococcus furiosus DNA/RNA-binding protein Alba protein (1-93AA)
Western Blot. Positive WB detected in Recombinant protein. All lanes: albA antibody at 3.4µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 27 kDa. Observed band size: 27 kDa..
Background:
Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes.
Synonyms:
DNA/RNA-binding protein Alba, albA
UniProt Protein Function:
Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes.
