ALAS1 Rabbit Monoclonal Antibody (CAB4817)
- SKU:
- CAB4817
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- ALAS
- ALAS-H
- ALAS3
- ALASH
- MIG4
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | ALAS1 Rabbit Monoclonal Antibody |
SKU: | CAB4817 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 541-640 of human ALAS1 (P13196). |
Sequence: | TEVC DELM SRHN IYVQ AINY PTVP RGEE LLRI APTP HHTP QMMN YFLE NLLV TWKQ VGLE LKPH SSAE CNFC RRPL HFEV MSER EKSY FSGL SKLV SAQA |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | ALAS; MIG4; ALAS3; ALASH; ALAS-H; ALAS1 |
Positive Sample: | HT-29,HepG2,SKOV3 |
Conjugate: | Unconjugated |
Cellular Localization: | Mitochondrion matrix. |
Calculated MW: | 71kDa |
Observed MW: | 70kDa |
This gene encodes the mitochondrial enzyme which is catalyzes the rate-limiting step in heme (iron-protoporphyrin) biosynthesis. The enzyme encoded by this gene is the housekeeping enzyme; a separate gene encodes a form of the enzyme that is specific for erythroid tissue. The level of the mature encoded protein is regulated by heme: high levels of heme down-regulate the mature enzyme in mitochondria while low heme levels up-regulate. A pseudogene of this gene is located on chromosome 12. Alternative splicing results in multiple transcript variants encoding different isoforms.
Purification Method: | Affinity purification |
Gene ID: | 211 |
Clone Number: | ARC0239 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |