ALAS1 Rabbit Polyclonal Antibody (CAB13462)
- SKU:
- CAB13462
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | ALAS1 Rabbit Polyclonal Antibody |
SKU: | CAB13462 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human ALAS1 (NP_954635.1). |
Sequence: | MESV VRRC PFLS RVPQ AFLQ KAGK SLLF YAQN CPKM MEVG AKPA PRAL STAA VHYQ QIKE TPPA SEKD KTAK AKVQ QTPD GSQQ SPDG TQLP SGHP LPAT SQGT ASKC PFLA AQMN QRGS SVFC KASL ELQE DVQE MNAV RKEV AETS AGPS VVSV KTDG GDPS GLLK NFQD IMQK QRPE RVSH LLQD NLPK SVST FQYD RFFE KKID EKKN DHTY RVFK TVNR RAHI FPMA DDYS DSLI TKKQ VSVW CS |
Tested Applications: | IF/ICC ELISA |
Recommended Dilution: | IF/ICC,1:50 - 1:200 |
Synonyms: | ALAS; MIG4; ALAS3; ALASH; ALAS-H; ALAS1 |
Conjugate: | Unconjugated |
Cellular Localization: | Mitochondrion matrix. |
Calculated MW: | 71kDa |
Observed MW: | Refer to figures |
This gene encodes the mitochondrial enzyme which is catalyzes the rate-limiting step in heme (iron-protoporphyrin) biosynthesis. The enzyme encoded by this gene is the housekeeping enzyme; a separate gene encodes a form of the enzyme that is specific for erythroid tissue. The level of the mature encoded protein is regulated by heme: high levels of heme down-regulate the mature enzyme in mitochondria while low heme levels up-regulate. A pseudogene of this gene is located on chromosome 12. Alternative splicing results in multiple transcript variants encoding different isoforms.
Purification Method: | Affinity purification |
Gene ID: | 211 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |