The AKT3 Polyclonal Antibody (CAB12909) is a valuable tool for researchers studying the AKT3 protein, a key player in cell signaling pathways that regulate cell growth, proliferation, and survival. This antibody, produced in rabbits, is highly specific to human samples and is suitable for use in Western blot applications. By targeting the AKT3 protein, this antibody allows for precise detection and analysis in a variety of cell types, making it an essential component of studies in oncology, neuroscience, and other areas of biomedical research.
AKT3, a member of the AKT protein kinase family, is involved in numerous cellular processes, including metabolism, angiogenesis, and cell migration. Dysregulation of AKT3 signaling has been implicated in diseases such as cancer, diabetes, and neurological disorders, making it a promising therapeutic target for drug development and precision medicine. By utilizing the AKT3 Polyclonal Antibody, researchers can gain valuable insights into the function and activity of AKT3, advancing our understanding of its role in health and disease.
Product Name:
AKT3 Rabbit Polyclonal Antibody
SKU:
CAB12909
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 90-190 of human AKT3 (NP_859029.1).
The protein encoded by this gene is a member of the AKT, also called PKB, serine/threonine protein kinase family. AKT kinases are known to be regulators of cell signaling in response to insulin and growth factors. They are involved in a wide variety of biological processes including cell proliferation, differentiation, apoptosis, tumorigenesis, as well as glycogen synthesis and glucose uptake. This kinase has been shown to be stimulated by platelet-derived growth factor (PDGF), insulin, and insulin-like growth factor 1 (IGF1). Alternatively splice transcript variants encoding distinct isoforms have been described.
Purification Method:
Affinity purification
Gene ID:
10000
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using AKT3 Rabbit pAb (CAB12909) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates / proteins: 25 μg per lane.Blocking buffer: 3 % nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 45s.
