The AKT2 Polyclonal Antibody (CAB1250) is a valuable tool for research into the AKT2 protein, known for its role in cell signaling pathways related to cell growth, metabolism, and survival. This antibody, generated in rabbits, exhibits high specificity for human samples and is optimized for use in Western blot applications. By binding to AKT2, it enables the detection and analysis of this important protein in various cell types, making it ideal for studies in cancer research and molecular biology.AKT2, a member of the AKT kinase family, is involved in key cellular processes such as cell proliferation and survival.
Dysregulation of AKT2 signaling has been linked to various diseases, including cancer, diabetes, and cardiovascular disorders. By studying the expression and activity of AKT2 using this antibody, researchers can gain valuable insights into the molecular mechanisms underlying these diseases and potential therapeutic targets for intervention.Overall, the AKT2 Polyclonal Antibody (CAB1250) is a reliable tool for investigating the function and regulation of AKT2 in normal and disease states, providing valuable information for the development of targeted therapies and diagnostic strategies in precision medicine.
Product Name:
Akt2 Rabbit Polyclonal Antibody
SKU:
CAB1250
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 100-200 of human Akt2 (NP_001617.1).
Cell membrane, Cytoplasm, Early endosome, Nucleus, Peripheral membrane protein.
Calculated MW:
56kDa
Observed MW:
60kDa
This gene is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains, which is involved in signaling pathways. The gene serves as an oncogene in the tumorigenesis of cancer cells For example, its overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. The encoded protein is a general protein kinase capable of phophorylating several known proteins, and has also been implicated in insulin signaling.
Purification Method:
Affinity purification
Gene ID:
208
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using Akt2 Rabbit pAb (CAB1250) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
