AKR7A2 Rabbit Polyclonal Antibody (CAB1227)
- SKU:
- CAB1227
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | AKR7A2 Rabbit Polyclonal Antibody |
SKU: | CAB1227 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 100-359 of human AKR7A2 (NP_003680.2). |
Sequence: | VKIA TKAN PWDG KSLK PDSV RSQL ETSL KRLQ CPQV DLFY LHAP DHGT PVEE TLHA CQRL HQEG KFVE LGLS NYAS WEVA EICT LCKS NGWI LPTV YQGM YNAT TRQV ETEL FPCL RHFG LRFY AYNP LAGG LLTG KYKY EDKD GKQP VGRF FGNS WAET YRNR FWKE HHFE AIAL VEKA LQAA YGAS APSV TSAA LRWM YHHS QLQG AHGD AVIL GMSS LEQL EQNL AATE EGPL EPAV VDAF NQAW HLVA HECP NYFR |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | AFAR; AKR7; AFAR1; AFB1-AR1; AKR7A2 |
Positive Sample: | Mouse kidney,Mouse testis,Mouse liver |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Golgi apparatus. |
Calculated MW: | 40kDa |
Observed MW: | 35kDa |
The protein encoded by this gene belongs to the aldo/keto reductase (AKR) superfamily and AKR7 family, which are involved in the detoxification of aldehydes and ketones. The AKR7 family consists of 3 genes that are present in a cluster on the p arm of chromosome 1. This protein, thought to be localized in the golgi, catalyzes the NADPH-dependent reduction of succinic semialdehyde to the endogenous neuromodulator, gamma-hydroxybutyrate. It may also function as a detoxication enzyme in the reduction of aflatoxin B1 and 2-carboxybenzaldehyde. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 8574 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |