AKR1C4 Rabbit Polyclonal Antibody (CAB7430)
- SKU:
- CAB7430
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | AKR1C4 Rabbit Polyclonal Antibody |
SKU: | CAB7430 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-323 of human AKR1C4 (NP_001809.3). |
Sequence: | MDPK YQRV ELND GHFM PVLG FGTY APPE VPRN RAVE VTKL AIEA GFRH IDSA YLYN NEEQ VGLA IRSK IADG SVKR EDIF YTSK LWCT FFQP QMVQ PALE SSLK KLQL DYVD LYLL HFPM ALKP GETP LPKD ENGK VIFD TVDL SATW EVME KCKD AGLA KSIG VSNF NCRQ LEMI LNKP GLKY KPVC NQVE CHPY LNQS KLLD FCKS KDIV LVAH SALG TQRH KLWV DPNS PVLL EDPV LCAL AKKH KRTP ALIA LRYQ LQRG VVVL AKSY NEQR IREN IQVF EFQL TSED MKVL DGLN RNYR YVVM DFLM DHPD YPFS DEY |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | C11; CDR; DD4; CHDR; DD-4; HAKRA; 3-alpha-HSD; AKR1C4 |
Positive Sample: | A-549,SW620,Mouse liver,Mouse lung,Rat liver |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm. |
Calculated MW: | 37kDa |
Observed MW: | 37kDa |
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the bioreduction of chlordecone, a toxic organochlorine pesticide, to chlordecone alcohol in liver. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.
Purification Method: | Affinity purification |
Gene ID: | 1109 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |