AKR1C2 Rabbit Polyclonal Antibody (CAB1048)
- SKU:
- CAB1048
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | AKR1C2 Rabbit Polyclonal Antibody |
SKU: | CAB1048 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-323 of human AKR1C2 (NP_995317.1). |
Sequence: | MDSK YQCV KLND GHFM PVLG FGTY APAE VPKS KALE AVKL AIEA GFHH IDSA HVYN NEEQ VGLA IRSK IADG SVKR EDIF YTSK LWSN SHRP ELVR PALE RSLK NLQL DYVD LYLI HFPV SVKP GEEV IPKD ENGK ILFD TVDL CATW EAME KCKD AGLA KSIG VSNF NHRL LEMI LNKP GLKY KPVC NQVE CHPY FNQR KLLD FCKS KDIV LVAY SALG SHRE EPWV DPNS PVLL EDPV LCAL AKKH KRTP ALIA LRYQ LQRG VVVL AKSY NEQR IRQN VQVF EFQL TSEE MKAI DGLN RNVR YLTL DIFA GPPN YPFS DEY |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:1000 - 1:5000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:100 |
Synonyms: | DD; DD2; TDD; BABP; DD-2; DDH2; HBAB; HAKRD; MCDR2; SRXY8; DD/BABP; AKR1C-pseudo; AKR1C2 |
Positive Sample: | Mouse kidney,Rat kidney |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm. |
Calculated MW: | 37kDa |
Observed MW: | 37kDa |
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols using NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme binds bile acid with high affinity, and shows minimal 3-alpha-hydroxysteroid dehydrogenase activity. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. Three transcript variants encoding two different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 1646 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |