The AKR1B1 Polyclonal Antibody (CAB1684) is a valuable tool for research involving AKR1B1, also known as aldose reductase, an enzyme involved in the metabolism of glucose and other sugars. This rabbit polyclonal antibody is highly specific and reacts strongly with human samples, making it ideal for use in Western blot applications.AKR1B1 is a key enzyme in the polyol pathway, which plays a role in diabetic complications, cancer, and inflammatory processes.
By targeting AKR1B1 with this antibody, researchers can investigate the role of this enzyme in various diseases and pathways, providing important insights for drug development and therapeutic interventions. Overall, the AKR1B1 Polyclonal Antibody (CAB1684) is a valuable tool for researchers studying the role of AKR1B1 in health and disease, offering reliable and specific detection in human samples for further understanding and advancements in the field.
Product Name:
AKR1B1 Rabbit Polyclonal Antibody
SKU:
CAB1684
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-316 of human AKR1B1 (NP_001619.1).
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. Multiple pseudogenes have been identified for this gene. The nomenclature system used by the HUGO Gene Nomenclature Committee to define human aldo-keto reductase family members is known to differ from that used by the Mouse Genome Informatics database.
Purification Method:
Affinity purification
Gene ID:
231
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates using AKR1B1 Rabbit pAb (CAB1684) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
