The AKR1A1 Polyclonal Antibody (CAB13577) is a research tool designed for investigating AKR1A1, an enzyme involved in the metabolism of a variety of compounds including steroids, aldehydes, and ketones. The antibody, produced in rabbits, exhibits high specificity for human samples and has been validated for use in Western blot applications. By binding to the AKR1A1 protein, this antibody enables accurate detection and analysis in different cell types, making it suitable for studies in metabolism, drug metabolism, and cancer research.
AKR1A1, also known as aldo-keto reductase 1A1, plays a crucial role in cellular detoxification and the protection against oxidative stress. Its involvement in metabolism makes it a potential target for research in diseases such as cancer, diabetes, and neurodegenerative disorders. Understanding the function and regulation of AKR1A1 is essential for developing therapeutic strategies that target its activity and impact various physiological processes.
Product Name:
AKR1A1 Rabbit Polyclonal Antibody
SKU:
CAB13577
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-325 of human AKR1A1 (NP_006057.1).
apical plasma membrane, cytosol, extracellular exosome, extracellular space
Calculated MW:
37kDa
Observed MW:
37kDa
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member, also known as aldehyde reductase, is involved in the reduction of biogenic and xenobiotic aldehydes and is present in virtually every tissue. Multiple alternatively spliced transcript variants of this gene exist, all encoding the same protein.
Purification Method:
Affinity purification
Gene ID:
10327
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using AKR1A1 Rabbit pAb (CAB13577) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.
