The AKIP1 Polyclonal Antibody (PACO00458) is a valuable tool for researchers studying AKIP1, a protein known to be involved in various cellular processes including cell migration, invasion, and proliferation. This antibody, raised in rabbits, demonstrates high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the AKIP1 protein, researchers can accurately detect and analyze AKIP1 expression in different cell types, making it an essential tool for studies in cancer research and cell biology.AKIP1, also known as A kinase interacting protein 1, is a critical player in signaling pathways that regulate cell growth, survival, and metastasis.
Its involvement in these processes positions it as a potential therapeutic target for cancer treatment and other diseases related to abnormal cell growth. Understanding the function of AKIP1 at the molecular level is essential for developing targeted therapies that can effectively modulate its activity in disease settings.Overall, the AKIP1 Polyclonal Antibody is a reliable and specific tool for researchers looking to deepen their understanding of AKIP1 biology and its implications in health and disease. With its versatile applications in different research areas, this antibody is sure to aid in groundbreaking discoveries and advancements in the field of molecular biology.
Antibody Name:
AKIP1 Antibody
Antibody SKU:
PACO00458
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB, IHC
Recommended Dilutions:
WB:1:500-1:2000, IHC:1:100-1:300
Species Reactivity:
Human
Immunogen:
synthesized peptide derived from the Internal region of human BCA3.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
AKIP1; BCA3; C11orf17; A-kinase-interacting protein 1; Breast cancer-associated gene 3 protein; PKA-interacting protein; Proline-rich protein BCA3
UniProt Protein Function:
BCA3: Enhances NF-kappa-B transcriptional activity by regulating the nuclear localization of the NF-kappa-B subunit RELA and promoting the phosphorylation of RELA by PRKACA. Regulates the effect of the cAMP-dependent protein kinase signaling pathway on the NF-kappa-B activation cascade. 3 isoforms of the human protein are produced by alternative splicing.Protein type: OncoproteinChromosomal Location of Human Ortholog: 11p15.3Cellular Component: nucleoplasmMolecular Function: protein binding
UniProt Protein Details:
NCBI Summary:
This gene encodes a nuclear protein that interacts with protein kinase A catalytic subunit, and regulates the effect of the cAMP-dependent protein kinase signaling pathway on the NF-kappa-B activation cascade. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Oct 2011]
