The AKAP8 Polyclonal Antibody (CAB3049) is a valuable tool for research involving AKAP8, a protein known for its role in regulating cell signaling pathways and gene expression. This antibody is raised in rabbits and is highly specific to AKAP8 in human samples, making it suitable for applications such as Western blotting.AKAP8, also known as A-kinase anchor protein 8, is involved in various cellular processes, including cell growth, differentiation, and apoptosis. By targeting AKAP8 with this antibody, researchers can study its function in different cell types and gain insights into its potential role in disease mechanisms.
With its high reactivity and specificity, the AKAP8 Polyclonal Antibody is an excellent tool for studies in molecular biology, cell signaling, and cancer research. Its ability to detect AKAP8 protein expression in a variety of experimental settings makes it a valuable asset for scientists aiming to unravel the complexities of cellular processes and identify potential therapeutic targets.
Product Name:
AKAP8 Rabbit Polyclonal Antibody
SKU:
CAB3049
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 480-692 of human AKAP8 (NP_005849.1).
This gene encodes a member of the A-kinase anchor protein family. A-kinase anchor proteins are scaffold proteins that contain a binding domain for the RI/RII subunit of protein kinase A (PKA) and recruit PKA and other signaling molecules to specific subcellular locations. This gene encodes a nuclear A-kinase anchor protein that binds to the RII alpha subunit of PKA and may play a role in chromosome condensation during mitosis by targeting PKA and the condensin complex to chromatin. A pseudogene of this gene is located on the short arm of chromosome 9.
Purification Method:
Affinity purification
Gene ID:
10270
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using AKAP8 Rabbit pAb (CAB3049) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
