The AKAP8 Polyclonal Antibody (CAB17302) is a powerful tool for researchers studying AKAP8, a protein known to be involved in various cellular processes, including regulation of gene expression, cell cycle progression, and DNA repair. This antibody, generated in rabbits, is specifically designed to target AKAP8 in human samples, making it an essential tool for Western blot applications.AKAP8, also known as A-kinase anchor protein 8, is a key player in cellular signaling pathways, particularly those involving protein kinase A (PKA) and other signaling molecules.
Its role in coordinating these pathways makes it a crucial target for research in fields such as cell biology, cancer biology, and signal transduction.By using the AKAP8 Polyclonal Antibody, researchers can accurately detect and analyze levels of AKAP8 protein in various cell types, allowing for a better understanding of its function and potential therapeutic applications. This antibody is an invaluable resource for studies aiming to unravel the complexities of AKAP8 and its impact on cellular processes.
Product Name:
AKAP8 Rabbit Polyclonal Antibody
SKU:
CAB17302
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 592-692 of human AKAP8 (NP_005849.1)
This gene encodes a member of the A-kinase anchor protein family. A-kinase anchor proteins are scaffold proteins that contain a binding domain for the RI/RII subunit of protein kinase A (PKA) and recruit PKA and other signaling molecules to specific subcellular locations. This gene encodes a nuclear A-kinase anchor protein that binds to the RII alpha subunit of PKA and may play a role in chromosome condensation during mitosis by targeting PKA and the condensin complex to chromatin. A pseudogene of this gene is located on the short arm of chromosome 9.
Purification Method:
Affinity purification
Gene ID:
10270
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using AKAP8 Rabbit pAb (CAB17302) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
