The AKAP7 Polyclonal Antibody (CAB11728) is a valuable tool for researchers studying AKAP7, a protein that plays a key role in cellular signaling and protein-protein interactions. This antibody, produced in rabbits, is highly specific and reactive with human samples, making it an ideal choice for Western blot applications.AKAP7, also known as A-kinase anchor protein 7, is involved in organizing signaling molecules within cells, particularly in the context of cyclic AMP signaling pathways. By targeting AKAP7 with this antibody, researchers can investigate its function and localization in various cell types, shedding light on its potential roles in processes such as cell growth, differentiation, and metabolism.
Given its importance in cellular signaling, AKAP7 is a promising target for research in fields such as cell biology, neuroscience, and cardiovascular disease. By using this antibody to study AKAP7 expression and regulation, researchers can gain insights into the underlying mechanisms of disease and potentially identify new therapeutic strategies.
Product Name:
AKAP7 Rabbit Polyclonal Antibody
SKU:
CAB11728
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-81 of human AKAP7 (NP_004833.1).
This gene encodes a member of the A-kinase anchoring protein (AKAP) family, a group of functionally related proteins that bind to a regulatory subunit (RII) of cAMP-dependent protein kinase A (PKA) and target the enzyme to specific subcellular compartments. AKAPs have a common RII-binding domain, but contain different targeting motifs responsible for directing PKA to distinct intracellular locations. Three alternatively spliced transcript variants encoding different isoforms have been described.
Purification Method:
Affinity purification
Gene ID:
9465
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using AKAP7 Rabbit pAb (CAB11728) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
