AKAP5 Rabbit Polyclonal Antibody (CAB6520)
- SKU:
- CAB6520
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | AKAP5 Rabbit Polyclonal Antibody |
SKU: | CAB6520 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human AKAP5 (NP_004848.3). |
Sequence: | METT ISEI HVEN KDEK RSAE GSPG AERQ KEKA SMLC FKRR KKAA KALK PKAG SEAA DVAR KCPQ EAGA SDQP EPTR GAWA SLKR LVTR RKRS ESSK QQKP LEGE MQPA INAE DADL SKKK AKSR LKIP CIKF PRGP KRSN HSKI IEDS DCSI KVQE EAEI LDIQ TQTP LNDQ ATKA KSTQ DLSE GISR KDGD EVCE SNVS NSTT SGEK VISV ELGL DNGH SAIQ TGTL ILEE IETI KEKQ DVQP QQAS PLET SETD HQQP VLSD VPPL PA |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:100 - 1:200 |
Synonyms: | H21; AKAP75; AKAP79; AKAP5 |
Positive Sample: | SH-SY5Y,HepG2,293T |
Conjugate: | Unconjugated |
Cellular Localization: | Lipid-anchor, Membrane. |
Calculated MW: | 47kDa |
Observed MW: | 47kDa |
The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein binds to the RII-beta regulatory subunit of PKA, and also to protein kinase C and the phosphatase calcineurin. It is predominantly expressed in cerebral cortex and may anchor the PKA protein at postsynaptic densities (PSD) and be involved in the regulation of postsynaptic events. It is also expressed in T lymphocytes and may function to inhibit interleukin-2 transcription by disrupting calcineurin-dependent dephosphorylation of NFAT.
Purification Method: | Affinity purification |
Gene ID: | 9495 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |