AKAP17A Antibody (PACO49090)
- SKU:
- PACO49090
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
AKAP17A Antibody (PACO49090)
The AKAP17A Polyclonal Antibody (PACO49090) is a powerful tool for researchers studying AKAP17A, a protein involved in cell signaling and organelle positioning. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in various applications, including Western blotting and immunofluorescence.AKAP17A, also known as A-kinase anchor protein 17A, is a scaffold protein that plays a key role in organizing protein complexes involved in signal transduction pathways. By targeting AKAP17A with this antibody, researchers can visualize and study its localization and interactions within the cell, providing valuable insights into its functions in various cellular processes.
The AKAP17A Polyclonal Antibody is a valuable tool for research in cell biology, molecular biology, and signal transduction pathways. Its specificity and reliability make it an ideal choice for investigating the role of AKAP17A in normal cellular function and disease states, offering new opportunities for understanding and potentially targeting this protein in therapeutic interventions.
| Antibody Name: | AKAP17A Antibody (PACO49090) |
| Antibody SKU: | PACO49090 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IF:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human A-kinase anchor protein 17A protein (1-350AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunofluorescence staining of 293 cells with PACO49090 at 1:166, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).. |
| Background: | Splice factor regulating alternative splice site selection for certain mRNA precursors. Mediates regulation of pre-mRNA splicing in a PKA-dependent manner. |
| Synonyms: | A-kinase anchor protein 17A (AKAP-17A) (721P) (B-lymphocyte antigen) (Protein XE7) (Protein kinase A-anchoring protein 17A) (PRKA17A) (Splicing factor, arginine/serine-rich 17A), AKAP17A, CXYorf3 DXYS155E SFRS17A XE7 |
| UniProt Protein Function: | SFRS17A: Splice factor regulating alternative splice site selection for certain mRNA precursors. Mediates regulation of pre- mRNA splicing in a PKA-dependent manner. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:RNA splicing Chromosomal Location of Human Ortholog: Xp22.33 and Yp11.32 Cellular Component: cytoplasm; nuclear speck; nucleoplasm; nucleus Molecular Function:protein binding; protein kinase A binding Biological Process: regulation of RNA splicing |
| NCBI Summary: | This locus encodes a protein kinase A anchoring protein. The encoded protein is part of the spliceosome complex and is involved in the regulation of alternate splicing in some mRNA precursors. Alternatively spliced transcript variants have been identified for this gene.[provided by RefSeq, Sep 2010] |
| UniProt Code: | Q02040 |
| NCBI GenInfo Identifier: | 146291102 |
| NCBI Gene ID: | 8227 |
| NCBI Accession: | Q02040.2 |
| UniProt Secondary Accession: | Q02040,Q02832, Q2TB98, Q5JQ74, Q5JQ76, Q8N6U9, |
| UniProt Related Accession: | Q02040 |
| Molecular Weight: | 51,409 Da |
| NCBI Full Name: | A-kinase anchor protein 17A |
| NCBI Synonym Full Names: | A-kinase anchoring protein 17A |
| NCBI Official Symbol: | AKAP17AÂ Â |
| NCBI Official Synonym Symbols: | XE7; 721P; XE7Y; CCDC133; CXYorf3; PRKA17A; SFRS17A; AKAP-17A; DXYS155EÂ Â |
| NCBI Protein Information: | A-kinase anchor protein 17A |
| UniProt Protein Name: | A-kinase anchor protein 17A |
| UniProt Synonym Protein Names: | 721P; B-lymphocyte antigen; Protein XE7; Protein kinase A-anchoring protein 17A; PRKA17A; Splicing factor, arginine/serine-rich 17A |
| Protein Family: | A-kinase anchor protein |
| UniProt Gene Name: | AKAP17AÂ Â |
| UniProt Entry Name: | AK17A_HUMAN |
| Antibodies | ELISA Kits |
| AKAP17A Antibody (PACO01704) | Human A-kinase anchor protein 17A / AKAP17A ELISA Kit |
| AKAP17A Antibody (PACO12146) | Human A-kinase anchor protein 17A (AKAP17A) ELISA Kit |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
Related Products
AKAP17A Antibody (PACO21819)
AKAP17A Antibody (PACO12146)
AKAP17A Antibody (PACO01704)
Human A-kinase anchor protein 17A / AKAP17A ELISA Kit (HUFI00952)
Human A-kinase anchor protein 17A (AKAP17A) ELISA Kit (HUEB1062)
OSTN Antibody (PACO64881)
OR9G1 Antibody (PACO64877)
