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AKAP17A Antibody (PACO12146)

SKU:
PACO12146
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Applications:
ELISA
WB
IHC
IF
Antibody Type:
Polyclonal Antibody
Conjugation:
Unconjugated
€459

Description

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AKAP17A Antibody (PACO12146)

The AKAP17A Polyclonal Antibody (PAC012146) is a crucial tool for researchers studying AKAP17A, a key protein involved in intracellular signaling and protein scaffolding. This antibody, generated in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. By binding to AKAP17A, this antibody allows for the detection and analysis of the protein in various cell types, making it an essential reagent for studies in cell biology and signal transduction pathways.AKAP17A, also known as A-kinase anchor protein 17A, has been shown to play a role in the regulation of protein kinase A (PKA) signaling, as well as in the organization of macromolecular signaling complexes within cells.

Research into the function of AKAP17A is important for understanding how intracellular signaling pathways are coordinated and regulated, and how dysregulation of these pathways can contribute to diseases such as cancer, cardiovascular disorders, and neurological conditions.By utilizing the AKAP17A Polyclonal Antibody (PAC012146), researchers can gain valuable insights into the role of AKAP17A in cellular physiology and disease processes, ultimately leading to the development of novel therapeutic strategies targeting intracellular signaling pathways regulated by this important protein.

Antibody Name:AKAP17A Antibody (PACO12146)
Antibody SKU:PACO12146
Size:50ul
Host Species:Rabbit
Tested Applications:ELISA, WB, IHC, IF
Recommended Dilutions:
Species Reactivity:Human
Immunogen:Human SFRS17A
Form:Liquid
Storage Buffer:PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Purification Method:Antigen Affinity Purified
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Synonyms:splicing factor, arginine/serine-rich 17A;SFRS17A;721P;CCDC133;CXYorf3;DXYS155E;MGC125365;MGC125366;MGC39904;XE7;XE7Y ;
UniProt Protein Function:SFRS17A: Splice factor regulating alternative splice site selection for certain mRNA precursors. Mediates regulation of pre- mRNA splicing in a PKA-dependent manner. 3 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:RNA splicing

Chromosomal Location of Human Ortholog: Xp22.33 and Yp11.32

Cellular Component: cytoplasm; nuclear speck; nucleoplasm; nucleus

Molecular Function:protein binding; protein kinase A binding

Biological Process: regulation of RNA splicing

NCBI Summary:This locus encodes a protein kinase A anchoring protein. The encoded protein is part of the spliceosome complex and is involved in the regulation of alternate splicing in some mRNA precursors. Alternatively spliced transcript variants have been identified for this gene.[provided by RefSeq, Sep 2010]
UniProt Code:Q02040
NCBI GenInfo Identifier:146291102
NCBI Gene ID:8227
NCBI Accession:Q02040.2
UniProt Secondary Accession:Q02040,Q02832, Q2TB98, Q5JQ74, Q5JQ76, Q8N6U9,
UniProt Related Accession:Q02040
Molecular Weight:51,409 Da
NCBI Full Name:A-kinase anchor protein 17A
NCBI Synonym Full Names:A-kinase anchoring protein 17A
NCBI Official Symbol:AKAP17A  
NCBI Official Synonym Symbols:XE7; 721P; XE7Y; CCDC133; CXYorf3; PRKA17A; SFRS17A; AKAP-17A; DXYS155E  
NCBI Protein Information:A-kinase anchor protein 17A
UniProt Protein Name:A-kinase anchor protein 17A
UniProt Synonym Protein Names:721P; B-lymphocyte antigen; Protein XE7; Protein kinase A-anchoring protein 17A; PRKA17A; Splicing factor, arginine/serine-rich 17A
Protein Family:A-kinase anchor protein
UniProt Gene Name:AKAP17A  
UniProt Entry Name:AK17A_HUMAN

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