AKAP17A Antibody (PACO01704)
- SKU:
- PACO01704
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
AKAP17A Antibody (PACO01704)
The AKAP17A Polyclonal Antibody (PACO01704) is a valuable tool for researchers studying AKAP17A, a protein known for its role in cellular signaling and molecular interactions. This antibody, produced through immunization of rabbits, exhibits high specificity and reactivity with human samples, making it suitable for a range of experimental applications.AKAP17A, a member of the A-kinase anchoring protein (AKAP) family, is involved in the organization of signaling complexes within cells, playing a critical role in processes such as cell division, gene expression, and neurotransmission. By targeting AKAP17A, researchers can gain insights into its functions and interactions, particularly in the context of signal transduction pathways and cellular responses.
This antibody is validated for use in Western blotting, immunohistochemistry, and other immunological techniques, enabling researchers to detect and analyze AKAP17A expression in various cell types and tissues. Its utility in studying AKAP17A makes it a valuable asset for investigations into cell signaling, neurobiology, and potential therapeutic targets for diseases such as cancer, neurological disorders, and cardiovascular conditions.
Antibody Name: | AKAP17A Antibody |
Antibody SKU: | PACO01704 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | WB:1:500-1:2000 |
Species Reactivity: | Human |
Immunogen: | synthesized peptide derived from the C-terminal region of human XE7. |
Form: | Liquid |
Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Synonyms: | AKAP17A; CXYorf3; DXYS155E; SFRS17A; XE7; A-kinase anchor protein 17A; AKAP-17A; 721P; B-lymphocyte antigen; Protein XE7; Protein kinase A-anchoring protein 17A; PRKA17A; Splicing factor; arginine/serine-rich 17A |
UniProt Protein Function: | SFRS17A: Splice factor regulating alternative splice site selection for certain mRNA precursors. Mediates regulation of pre- mRNA splicing in a PKA-dependent manner. 3 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:RNA splicing Chromosomal Location of Human Ortholog: Xp22.33 and Yp11.32 Cellular Component: cytoplasm; nuclear speck; nucleoplasm; nucleus Molecular Function:protein binding; protein kinase A binding Biological Process: regulation of RNA splicing |
NCBI Summary: | This locus encodes a protein kinase A anchoring protein. The encoded protein is part of the spliceosome complex and is involved in the regulation of alternate splicing in some mRNA precursors. Alternatively spliced transcript variants have been identified for this gene.[provided by RefSeq, Sep 2010] |
UniProt Code: | Q02040 |
NCBI GenInfo Identifier: | 146291102 |
NCBI Gene ID: | 8227 |
NCBI Accession: | Q02040.2 |
UniProt Secondary Accession: | Q02040,Q02832, Q2TB98, Q5JQ74, Q5JQ76, Q8N6U9, |
UniProt Related Accession: | Q02040 |
Molecular Weight: | 51,409 Da |
NCBI Full Name: | A-kinase anchor protein 17A |
NCBI Synonym Full Names: | A-kinase anchoring protein 17A |
NCBI Official Symbol: | AKAP17AÂ Â |
NCBI Official Synonym Symbols: | XE7; 721P; XE7Y; CCDC133; CXYorf3; PRKA17A; SFRS17A; AKAP-17A; DXYS155EÂ Â |
NCBI Protein Information: | A-kinase anchor protein 17A |
UniProt Protein Name: | A-kinase anchor protein 17A |
UniProt Synonym Protein Names: | 721P; B-lymphocyte antigen; Protein XE7; Protein kinase A-anchoring protein 17A; PRKA17A; Splicing factor, arginine/serine-rich 17A |
Protein Family: | A-kinase anchor protein |
UniProt Gene Name: | AKAP17AÂ Â |
UniProt Entry Name: | AK17A_HUMAN |