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AK6 Antibody (PACO00382)

SKU:
PACO00382
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Applications:
ELISA
WB
IHC
IF
Antibody Type:
Polyclonal Antibody
Conjugation:
Unconjugated
€319

Description

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AK6 Antibody (PACO00382)

The AK6 Antibody (PACO00382) is a polyclonal antibody specifically designed for research involving the AK6 protein. The antibody is raised in rabbits and is highly reactive with human samples, making it an ideal tool for studies in immunology and cancer research. Validated for use in Western blot applications, this antibody binds to the AK6 protein, allowing for detection and analysis in various cell types.AK6, a cell surface molecule, is known to play a key role in immune regulation, particularly in inhibiting immune responses. Its involvement in immune modulation makes it a valuable target for research into diseases such as cancer, autoimmune disorders, and chronic inflammatory conditions.

Understanding the function of AK6 is crucial for developing therapies that target or modulate immune function in these disease contexts.Overall, the AK6 Antibody (PACO00382) is a valuable tool for researchers studying immune regulation and its implications in various diseases, providing important insights that can contribute to the development of novel therapeutic strategies.

Antibody Name:AK6 Antibody
Antibody SKU:PACO00382
Size:50ug
Host Species:Rabbit
Tested Applications:ELISA, WB, IHC, IF
Recommended Dilutions:WB:1:500-1:2000, IHC:1:100-1:300, IF:1:200-1:1000
Species Reactivity:Human, Mouse, Rat
Immunogen:synthesized peptide derived from the N-terminal region of human AK6.
Form:Liquid
Storage Buffer:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Synonyms:TAF9; AK6; CINAP; AD-004; CGI-137; Adenylate kinase isoenzyme 6; ATP-AMP transphosphorylase 6; Coilin-interacting nuclear ATPase protein; hCINAP
UniProt Protein Function:TAFII31 iso2: a component of the transcription factor IID (TFIID) complex, PCAF histone acetylase complex and TBP-free TAFII complex (TFTC). TIIFD is essential for mediating regulation of RNA polymerase transcription. TAFII31 binds to p53, the basal transcription factor GTF2B, and the acidic transactivator viral protein 16 (VP16). It is a coactivator for P53. Protein type: Acetyltransferase; Kinase, other; Transcription initiation complex; DNA-binding; EC 2.7.4.3Chromosomal Location of Human Ortholog: 5q13.2Cellular Component: nucleoplasm; PCAF complex; transcription factor TFIID complexMolecular Function: ATPase binding; DNA binding; histone acetyltransferase activity; p53 binding; protein binding; protein heterodimerization activity; transcription activator binding; transcription coactivator activityBiological Process: box C/D snoRNP assembly; establishment and/or maintenance of chromatin architecture; gene expression; negative regulation of apoptosis; negative regulation of proteasomal ubiquitin-dependent protein catabolic process; positive regulation of cell growth; positive regulation of transcription from RNA polymerase II promoter; protein stabilization; response to DNA damage stimulus; RNA elongation from RNA polymerase II promoter; transcription from RNA polymerase II promoter; transcription initiation from RNA polymerase II promoter; viral reproduction
UniProt Protein Details:
NCBI Summary:This gene encodes a protein that belongs to the adenylate kinase family of enzymes. The protein has a nuclear localization and contains Walker A (P-loop) and Walker B motifs and a metal-coordinating residue. The protein may be involved in regulation of Cajal body formation. In human, AK6 and TAF9 (GeneID: 6880) are two distinct genes that share 5' exons. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
UniProt Code:Q9Y3D8
NCBI GenInfo Identifier:6831735
NCBI Gene ID:102157402
NCBI Accession:Q9Y3D8.1
UniProt Secondary Accession:Q9Y3D8,Q5F2S9, A8MSZ6
UniProt Related Accession:Q9Y3D8
Molecular Weight:19,805 Da
NCBI Full Name:Adenylate kinase isoenzyme 6
NCBI Synonym Full Names:adenylate kinase 6
NCBI Official Symbol:AK6  
NCBI Official Synonym Symbols:CIP; CINAP; AD-004; hCINAP; CGI-137  
NCBI Protein Information:adenylate kinase isoenzyme 6
UniProt Protein Name:Adenylate kinase isoenzyme 6
UniProt Synonym Protein Names:Adrenal gland protein AD-004; Coilin-interacting nuclear ATPase protein
Protein Family:Adenylate kinase
UniProt Gene Name:AK6  
UniProt Entry Name:KAD6_HUMAN

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