AK2 Monoclonal Antibody [PAT7E7AT] (CPAB0220)
- SKU:
- CPAB0220
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Mouse
Description
AK2 Monoclonal Antibody [PAT7E7AT] (CPAB0220)
The AK2 Polyclonal Antibody (CPAB0220) is a crucial tool for researchers studying the AK2 protein, a key enzyme involved in energy metabolism and cell survival. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications, enabling easy detection and analysis of AK2 in various cell types.AK2 is known for its role in the regulation of cellular energy production through the maintenance of mitochondrial function. Dysregulation of AK2 has been linked to various diseases, including mitochondrial disorders and cancer.
By targeting AK2 with this antibody, researchers can gain insights into its functions and potential therapeutic applications in these disease contexts.The AK2 Polyclonal Antibody is a valuable asset for researchers in the fields of cell biology, biochemistry, and cancer research. Its ability to specifically bind to AK2 protein offers a powerful tool for investigating the molecular mechanisms underlying cellular energy metabolism and survival, paving the way for potential therapeutic interventions targeting AK2 in disease prevention and treatment.
Product Name: | AK2 Antibody |
Product Sku: | CPAB0220 |
Size: | 5μg |
Host Species: | Mouse IgG1 |
Immunogen: | Anti-human AK2 mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human AK2 protein 1-239 amino acids purified from Ecoli. |
Clone: | PAT7E7AT. |
Reactivity: | Human |
Applications: | ELISA, Flow Cytometry |
Purification Method: | AK2 antibody was purified from mouse ascitic fluids by protein-A affinity chromatography. |
Isotype: | |
Background: | Adenylate kinases plays a role in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate groups among adenine nucleotides. There are 3 types of adenylate kinase isozymes, AK1, AK2, and AK3 in vertebrates. Expression of these isozymes are tissue-specific and developmentally regulated. AK2 is localized in the mitochondrial intermembrane space and is involved in apoptosis. AK2 is mutated in individuals with reticular dysgenesis. |
Synonyms: | ADK2, AK-2, Adenylate kinase isoenzyme 2 mitochondrial, ATP-AMP transphosphorylase 2, adenylate kinase 2. |
Storage Buffer: | For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. |