The Ajuba Polyclonal Antibody is a valuable tool for research involving Ajuba, a protein that plays a role in cell adhesion, migration, and signal transduction. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to Ajuba, researchers can study its function and expression in a variety of cell types, making it ideal for investigations in cell biology and cancer research.
Ajuba is a key player in cellular processes such as cell adhesion and migration, making it an intriguing target for studies on cancer metastasis and tissue development. Its involvement in signal transduction pathways also suggests a potential role in regulating cell growth and proliferation. By studying Ajuba's function, researchers can gain insights into its potential as a therapeutic target for conditions like cancer and developmental disorders.
Product Name:
Ajuba Polyclonal Antibody
SKU:
CAB21760
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 201-290 of human Ajuba (NP_116265.1).
Enables alpha-catenin binding activity and transcription corepressor activity. Involved in several processes, including negative regulation of hippo signaling; positive regulation of gene silencing by miRNA; and regulation of cellular response to hypoxia. Acts upstream of or within gene silencing by miRNA and positive regulation of protein-containing complex assembly. Located in several cellular components, including Golgi apparatus; P-body; and nucleoplasm.
Purification Method:
Affinity purification
Gene ID:
84962
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of HepG2, using Ajuba Rabbit pAb antibody (CAB21760) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
