The AIP Polyclonal Antibody (CAB9852) is a valuable tool for researchers studying the AIP protein, a key regulator of cellular homeostasis and cell growth. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications, allowing for the detection and analysis of AIP protein levels in various cell types.AIP, also known as aryl hydrocarbon receptor-interacting protein, plays a crucial role in modulating the activity of the aryl hydrocarbon receptor (AhR), a transcription factor involved in regulating gene expression in response to environmental toxins and endogenous ligands.
Dysregulation of AIP expression has been linked to various diseases, including cancer and endocrine disorders, making it a promising target for therapeutic interventions.By using the AIP Polyclonal Antibody, researchers can explore the mechanisms of AIP function and its impact on cellular processes, ultimately advancing our understanding of disease pathogenesis and paving the way for the development of novel treatments targeting AIP-associated conditions.
Product Name:
AIP Rabbit Polyclonal Antibody
SKU:
CAB9852
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-330 of human AIP (NP_003968.3).
The protein encoded by this gene is a receptor for aryl hydrocarbons and a ligand-activated transcription factor. The encoded protein is found in the cytoplasm as part of a multiprotein complex, but upon binding of ligand is transported to the nucleus. This protein can regulate the expression of many xenobiotic metabolizing enzymes. Also, the encoded protein can bind specifically to and inhibit the activity of hepatitis B virus. Three transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
9049
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using AIP antibody (CAB9852) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.
