The AIP Polyclonal Antibody (CAB12546) is a valuable tool for researchers studying the AIP protein, a key player in cellular processes related to immune regulation. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By targeting the AIP protein, this antibody enables precise detection and analysis in a variety of cell types, making it an essential component for studies in immunology and cancer research.AIP, also known as aryl hydrocarbon receptor-interacting protein, is involved in controlling immune responses and has been implicated in various diseases such as cancer, autoimmune disorders, and chronic inflammatory conditions.
Understanding the function of AIP is crucial for uncovering its role in these pathological processes and developing targeted therapies that modulate immune function. The AIP Polyclonal Antibody is a reliable tool for researchers seeking to unravel the complex mechanisms underlying immune regulation and disease pathogenesis.
Product Name:
AIP Rabbit Polyclonal Antibody
SKU:
CAB12546
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-330 of human AIP (NP_003968.3).
B cells,SH-SY5Y,Raji,MCF7,SW620,Mouse kidney,Mouse pancreas,Rat liver
Conjugate:
Unconjugated
Cellular Localization:
Cytoplasm.
Calculated MW:
38kDa
Observed MW:
37kDa
The protein encoded by this gene is a receptor for aryl hydrocarbons and a ligand-activated transcription factor. The encoded protein is found in the cytoplasm as part of a multiprotein complex, but upon binding of ligand is transported to the nucleus. This protein can regulate the expression of many xenobiotic metabolizing enzymes. Also, the encoded protein can bind specifically to and inhibit the activity of hepatitis B virus. Three transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
9049
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using AIP antibody (CAB12546) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.
