AIMP1 Rabbit Polyclonal Antibody (CAB5301)
- SKU:
- CAB5301
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cardiovascular
Frequently bought together:
Description
Product Name: | AIMP1 Rabbit Polyclonal Antibody |
SKU: | CAB5301 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 25-180 of human AIMP1 (NP_001135888.1). |
Sequence: | MANN DAVL KRLE QKGA EADQ IIEY LKQQ VSLL KEKA ILQA TLRE EKKL RVEN AKLK KEIE ELKQ ELIQ AEIQ NGVK QIPF PSGT PLHA NSMV SENV IQST AVTT VSSG TKEQ IKGG TGDE KKAK EKIE KKGE KKEK KQQS IAGS ADSK PIDV SRLD |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 |
Synonyms: | p43; HLD3; EMAP2; SCYE1; EMAPII; AIMP1 |
Positive Sample: | HL-60,22RV1,HepG2,HT-29,MCF7,A-549 |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Cytoplasmic vesicle, Endoplasmic reticulum, Golgi apparatus, Nucleus, Secreted, cytosol, secretory vesicle. |
Calculated MW: | 34kDa |
Observed MW: | 37kDa |
The protein encoded by this gene is a cytokine that is specifically induced by apoptosis, and it is involved in the control of angiogenesis, inflammation, and wound healing. The release of this cytokine renders the tumor-associated vasculature sensitive to tumor necrosis factor. The precursor protein is identical to the p43 subunit, which is associated with the multi-tRNA synthetase complex, and it modulates aminoacylation activity of tRNA synthetase in normal cells. This protein is also involved in the stimulation of inflammatory responses after proteolytic cleavage in tumor cells. Multiple transcript variants encoding different isoforms have been found for this gene. A pseudogene has been identified on chromosome 20.
Purification Method: | Affinity purification |
Gene ID: | 9255 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |