The AIMP1 Polyclonal Antibody (CAB5301) is a valuable tool for researchers studying AIMP1, a protein involved in immune regulation and inflammatory responses. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the AIMP1 protein, this antibody enables the detection and analysis of AIMP1 in various cell types, making it ideal for research in immunology and inflammatory disorders.AIMP1, also known as aminoacyl tRNA synthetase complex-interacting multifunctional protein 1, plays a crucial role in regulating immune responses and inflammation.
Its involvement in inflammatory pathways and immune system modulation makes it a promising target for studies on conditions such as autoimmune diseases, cancer, and chronic inflammatory disorders. Understanding the function and regulation of AIMP1 could provide insights into potential therapeutic interventions for these conditions.
Product Name:
AIMP1 Rabbit Polyclonal Antibody
SKU:
CAB5301
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 25-180 of human AIMP1 (NP_001135888.1).
The protein encoded by this gene is a cytokine that is specifically induced by apoptosis, and it is involved in the control of angiogenesis, inflammation, and wound healing. The release of this cytokine renders the tumor-associated vasculature sensitive to tumor necrosis factor. The precursor protein is identical to the p43 subunit, which is associated with the multi-tRNA synthetase complex, and it modulates aminoacylation activity of tRNA synthetase in normal cells. This protein is also involved in the stimulation of inflammatory responses after proteolytic cleavage in tumor cells. Multiple transcript variants encoding different isoforms have been found for this gene. A pseudogene has been identified on chromosome 20.
Purification Method:
Affinity purification
Gene ID:
9255
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using AIMP1 Rabbit pAb (CAB5301) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
