The AIM2 Polyclonal Antibody (CAB3356) is a valuable tool for researchers studying AIM2, a key protein involved in the regulation of immune responses and inflammation. This antibody, produced through immunization of rabbits, exhibits high reactivity with human samples, making it an ideal choice for use in Western blot applications. By specifically binding to the AIM2 protein, this antibody enables precise detection and analysis in various cell types, allowing for in-depth investigations in the fields of immunology and cancer research.AIM2, also known as absent in melanoma 2, plays a crucial role in immune surveillance and inflammatory responses by detecting cytoplasmic DNA and initiating the inflammasome pathway.
Dysfunction of AIM2 has been implicated in various diseases, including autoimmune disorders, infectious diseases, and cancer. By studying the mechanisms underlying AIM2 activity, researchers can gain valuable insights into the development of targeted therapies for such conditions.In summary, the AIM2 Polyclonal Antibody (CAB3356) serves as a vital tool for researchers seeking to unravel the complexities of immune responses, inflammation, and disease pathogenesis. Its high specificity and reliability make it an indispensable resource for studies aimed at advancing our understanding of AIM2 and its role in health and disease.
Product Name:
AIM2 Rabbit Polyclonal Antibody
SKU:
CAB3356
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 130-337 of human AIM2 (NP_004824.1).
AIM2 is a member of the IFI20X /IFI16 family. It plays a putative role in tumorigenic reversion and may control cell proliferation. Interferon-gamma induces expression of AIM2.
Purification Method:
Affinity purification
Gene ID:
9447
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using AIM2 antibody (CAB3356) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
