The AIFM2 Polyclonal Antibody (CAB12128) is a specialized tool for researchers studying the AIFM2 protein, which is involved in mitochondrial function and energy metabolism. This rabbit-derived antibody is highly specific to human samples and has been validated for use in Western blot applications. By targeting the AIFM2 protein, this antibody allows for precise detection and analysis in various cell types, making it ideal for studies related to mitochondrial dysfunction, metabolism, and cell death pathways.AIFM2, also known as a putative mitochondrial inner membrane protein, plays a critical role in maintaining mitochondrial integrity and function.
Dysregulation of AIFM2 has been implicated in various diseases, including neurodegenerative disorders, metabolic syndromes, and cancer. Research into the role of AIFM2 is crucial for understanding mitochondrial dysfunction and exploring potential therapeutic strategies to target this pathway.By utilizing the AIFM2 Polyclonal Antibody (CAB12128), researchers can further investigate the role of AIFM2 in cellular processes, mitochondrial dynamics, and disease pathology. This antibody offers a valuable tool for advancing research in the fields of mitochondria biology, energy metabolism, and personalized medicine.
Product Name:
AIFM2 Rabbit Polyclonal Antibody
SKU:
CAB12128
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 43-371 of human AIFM2/FSP1/AMID/AMID (NP_116186.1).
This gene encodes a flavoprotein oxidoreductase that binds single stranded DNA and is thought to contribute to apoptosis in the presence of bacterial and viral DNA. The expression of this gene is also found to be induced by tumor suppressor protein p53 in colon cancer cells.
Purification Method:
Affinity purification
Gene ID:
84883
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of lysates from HepG2 cells, using AIFM2/FSP1 Rabbit pAb (CAB12128) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 180s.
