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AIFM1 Monoclonal Antibody [PAT22E9AT] (CPAB0652)

SKU:
CPAB0652
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Universal
Host Species:
Mouse
Isotype:
IgG1
Clone:
PAT22E9AT
Applications:
ELISA
FC
€149
Frequently bought together:

Description

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AIFM1 Monoclonal Antibody [PAT22E9AT] (CPAB0652)

The AIFM1 Polyclonal Antibody (CPAB0652) is a valuable tool for researchers studying AIFM1, a protein involved in mitochondrial dynamics and apoptosis. This antibody, generated in rabbits, specifically targets human samples and has been validated for use in Western blot applications. By binding to the AIFM1 protein, this antibody allows for the detection and analysis of AIFM1 in various cell types, making it ideal for research in the fields of cell biology and apoptosis.

AIFM1, also known as apoptosis-inducing factor, plays a crucial role in regulating programmed cell death and maintaining mitochondrial function. Dysregulation of AIFM1 has been implicated in various diseases, including neurodegenerative disorders and cancer. By investigating the function of AIFM1, researchers can gain insights into the mechanisms of cell death and potentially develop novel therapeutic strategies for treating related diseases.

Product Name:AIFM1 Antibody
Product Sku:CPAB0652
Size:5μg
Host Species:Mouse
Immunogen:Anti-human AIFM1 mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human AIFM1 protein 98-69 amino acids purified from Ecoli.
Clone:PAT22E9AT.
Reactivity:Other bodies
Applications:ELISA, Flow Cytometry
Purification Method:AIFM1 antibody was purified from mouse ascitic fluids by protein-A affinity chromatography.
Isotype:IgG1
Background:Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1) is a mitochondrial protein which translocates to the nucleus once apoptosis has been initiated. AIFM1 causes DNA fragmentation and chromatin condensation and also triggers the release of cytochrome c and caspase-9 from mitochondria. Bcl-2 overexpression prevents the release of AIFM1 from mitochondria, but doesn't block its apoptogenic activity.
Synonyms:Apoptosis-inducing factor 1, mitochondrial, Programmed cell death protein 8, AIFM1, AIF, PDCD8, CMTX4, COWCK, COXPD6, isoform 2 precursor, Apoptosis-Inducing Factor, Mitochondrion-Associated, 1.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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