The AIF1 Polyclonal Antibody (CAB12391) is a valuable tool for researchers studying AIF1, a protein involved in immune regulation and inflammation. This antibody, produced in rabbits, is highly specific and reactive towards human samples, making it ideal for applications such as Western blot analysis. By binding to the AIF1 protein, this antibody allows for the detection and analysis of AIF1 in various cell types, making it essential for studies in immunology and inflammatory diseases.
AIF1, also known as allograft inflammatory factor 1, is a protein that plays a crucial role in immune response modulation and inflammatory processes. Understanding the function of AIF1 is essential for uncovering its role in diseases such as cancer, autoimmune disorders, and chronic inflammatory conditions. By targeting AIF1, researchers can develop new therapies aimed at modulating immune responses and treating inflammatory diseases effectively.
Product Name:
Iba1 Rabbit Polyclonal Antibody
SKU:
CAB12391
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-147 of human AIF1/IBA1 (NP_001614.3).
This gene encodes a protein that binds actin and calcium. This gene is induced by cytokines and interferon and may promote macrophage activation and growth of vascular smooth muscle cells and T-lymphocytes. Polymorphisms in this gene may be associated with systemic sclerosis. Alternative splicing results in multiple transcript variants, but the full-length and coding nature of some of these variants is not certain.
Purification Method:
Affinity purification
Gene ID:
199
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of lysates from THP-1 cells, using AIF1/IBA1 Rabbit pAb (CAB12391) at 1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
