null

AICDA Monoclonal Antibody [P2D3AT] (CPAB0157)

SKU:
CPAB0157
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG1
Clone:
P2D3AT
Applications:
WB
ELISA
€149
Frequently bought together:

Description

system_update_alt Datasheet

AICDA Monoclonal Antibody [P2D3AT] (CPAB0157)

The AICDA Polyclonal Antibody (CPAB0157) is a vital tool for researchers studying AICDA, a key enzyme involved in somatic hypermutation and class switch recombination in B cells. This antibody, produced in rabbits, exhibits high reactivity with human samples and is optimized for Western blot applications. By specifically binding to the AICDA protein, researchers can accurately detect and analyze its expression in a variety of cell types, making it an essential component for studies in immunology and cancer research.

AICDA, also known as activation-induced cytidine deaminase, is crucial for generating diversity in the antibody response by inducing mutations in immunoglobulin genes. Its role in shaping the adaptive immune response makes it a valuable target for investigating diseases such as lymphomas, autoimmune disorders, and infectious diseases. Understanding the function of AICDA is essential for developing targeted therapies that manipulate the immune response in these pathological conditions.

Product Name:AICDA Antibody
Product Sku:CPAB0157
Size:5μg
Host Species:Mouse
Immunogen:Anti-human AICDA mAb, is derived from hybridization of mouse SP2/ myeloma cells with spleen cells from BALB/c mice immunized with recombinant human AICDA amino acids 1-54 purified from Ecoli.
Clone:P2D3AT.
Reactivity:Human
Applications:Western Blot, ELISA
Purification Method:AICDA antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
Isotype:IgG1
Background:AICDA is an RNA-editing deaminase which belongs to the cytidine deaminase family. AICDA is involved in somatic hypermutation, gene conversion, and class-switch recombination of immunoglobulin genes. Defects in the AICDA gene are the cause of autosomal recessive hyper-IgM immunodeficiency syndrome type 2 (HIGM2).
Synonyms:Activation-induced cytidine deaminase, Cytidine aminohydrolase, AICDA, AID, ARP2, CDA2, HIGM2.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

Related Products