The AHA1 Rabbit Monoclonal Antibody (CAB9538) is a high-quality antibody designed for research involving the AHA1 protein, a key regulator of HSP90 chaperone activity. This antibody, generated in rabbits, is highly specific and reactive with human samples, making it a valuable tool for studying the function and regulation of AHA1 in various biological processes.AHA1 is a co-chaperone protein that interacts with HSP90 to modulate its ATPase activity, thereby regulating the activity of HSP90 client proteins involved in processes such as cell signaling, protein folding, and cell cycle regulation. Understanding the role of AHA1 in these pathways is essential for unraveling its potential implications in diseases such as cancer, neurodegenerative disorders, and autoimmune conditions.
The AHA1 Rabbit Monoclonal Antibody (CAB9538) has been validated for use in Western blot applications, enabling the detection and analysis of AHA1 in different cell types and tissues. Its high specificity and sensitivity make it an ideal tool for researchers in the fields of molecular biology, cell biology, and biochemistry who are interested in unraveling the intricate mechanisms of protein folding and chaperone regulation.
Product Name:
AHA1 Rabbit Monoclonal Antibody
SKU:
CAB9538
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 239-338 of human AHA1 (O95433).
Enables ATPase activator activity; Hsp90 protein binding activity; and chaperone binding activity. Involved in positive regulation of ATPase activity. Located in cytosol.
Purification Method:
Affinity purification
Gene ID:
10598
Clone Number:
ARC1623
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using AHA1 Rabbit mAb (CAB9538) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
