The AHNAK2 Polyclonal Antibody (PACO58272) is a valuable tool for researchers studying AHNAK2, a protein involved in cell adhesion, migration, and signaling. This antibody is produced in rabbits and exhibits high reactivity with human samples, making it ideal for use in Western blot applications. By specifically binding to AHNAK2, this antibody enables precise detection and analysis in a variety of cell types.AHNAK2 plays a crucial role in various cellular processes, including cell motility and adhesion, making it a potentially important target for research in areas such as cancer progression and metastasis.
By studying the function and regulation of AHNAK2, researchers can gain valuable insights into cellular behavior and potential therapeutic strategies.Overall, the AHNAK2 Polyclonal Antibody (PACO58272) is a valuable tool for investigating the role of AHNAK2 in cellular processes and disease, making it a valuable asset for studies in cell biology, cancer research, and beyond.
IHC image of PACO58272 diluted at 1:400 and staining in paraffin-embedded human liver cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
Immunofluorescence staining of A549 cells with PACO58272 at 1:133, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
IHC image of PACO58272 diluted at 1:400 and staining in paraffin-embedded human brain tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
This gene encodes a large nucleoprotein. The encoded protein has a tripartite domain structure with a relatively short N-terminus and a long C-terminus, separated by a large body of repeats. The N-terminal PSD-95/Discs-large/ZO-1 (PDZ)-like domain is thought to function in the formation of stable homodimers. The encoded protein may play a role in calcium signaling by associating with calcium channel proteins. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2017]
