AHA1 Monoclonal Antibody [PAT3E9AT] (CPAB0293)
- SKU:
- CPAB0293
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Mouse
- Isotype:
- IgG2b
- Clone:
- PAT3E9AT
- Applications:
- WB
- ELISA
Description
AHA1 Monoclonal Antibody [PAT3E9AT] (CPAB0293)
The AHA1 Polyclonal Antibody (CPAB0293) is a valuable tool for researchers studying the AHA1 protein, a co-chaperone involved in protein folding and quality control processes. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the AHA1 protein, this antibody allows for accurate detection and analysis in a variety of cell types, making it suitable for research in molecular biology and cancer biology.AHA1, also known as activator of HSP90 ATPase homolog 1, plays a crucial role in the regulation of heat shock proteins and protein folding pathways.
Its involvement in protein quality control processes makes it a potential target for investigation in diseases such as cancer, neurodegenerative disorders, and protein misfolding diseases. Understanding the function of AHA1 is important for developing interventions that target protein folding mechanisms and proteostasis in disease states.Overall, the AHA1 Polyclonal Antibody (CPAB0293) offers researchers a reliable tool for studying the role of the AHA1 protein in cellular processes, with potential implications for therapeutic development in various disease contexts.
Product Name: | AHA1 Antibody |
Product Sku: | CPAB0293 |
Size: | 5μg |
Host Species: | Mouse |
Immunogen: | Anti-human AHA1 mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human AHA1 protein 19-337 amino acids purified from Ecoli. |
Clone: | PAT3E9AT. |
Reactivity: | Human |
Applications: | Western Blot, ELISA |
Purification Method: | AHA1 antibody was purified from mouse ascitic fluids by protein-A affinity chromatography. |
Isotype: | IgG2b |
Background: | AHA1 is a cochaperone that stimulates hsp90 ATPase activity. AHSA1 binds the middle domain of Hsp90 (amino acid 272-627) and functions as an ATPase-activating protein that competes with p23 and other co-chaperones for Hsp90 binding. AHA1 affects a step in the endoplasmic reticulum to golgi trafficking. |
Synonyms: | AHSA1, ACA1, p38, C14orf3, Activator of HSP90 ATPase-1. |
Storage Buffer: | For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. |