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AGXT Monoclonal Antibody [PAT2T4AT] (CPAB0168)

SKU:
CPAB0168
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG2b
Clone:
PAT2T4AT
Applications:
IF
ELISA
€149
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Description

system_update_alt Datasheet

AGXT Monoclonal Antibody [PAT2T4AT] (CPAB0168)

The AGXT Polyclonal Antibody (CPAB0168) is a valuable tool for researchers studying AGXT, a key enzyme involved in the metabolism of amino acids, specifically the conversion of glyoxylate to glycine. This antibody, produced in rabbits, is highly specific to human AGXT and has been validated for use in Western blot applications. By targeting the AGXT protein, this antibody enables researchers to accurately detect and analyze AGXT levels in various cell types, making it an essential component for studies in metabolism, kidney function, and rare genetic disorders.AGXT plays a crucial role in maintaining proper amino acid balance in the body, making it a relevant target for research into conditions such as primary hyperoxaluria, a rare genetic disorder characterized by excessive oxalate production.

By understanding the function and regulation of AGXT, researchers can gain insights into the mechanisms underlying these disorders and potentially identify new therapeutic approaches for their treatment. The AGXT Polyclonal Antibody is a valuable tool for advancing our understanding of amino acid metabolism and its implications for human health.

Product Name:AGXT Antibody
Product Sku:CPAB0168
Size:5μg
Host Species:Mouse
Immunogen:Anti-human AGXT mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with recombinant human AGXT amino acids 33-392 purified from Ecoli.
Clone:PAT2T4AT.
Reactivity:Human
Applications:Immunofluorescence, ELISA
Purification Method:AGXT antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
Isotype:IgG2b
Background:AGXT is expressed only in the liver and its protein is localized mostly in the peroxisomes, where it is involved in glyoxylate detoxification. Mutations in the AGXT gene, some of which alter subcellular targetting, have been linked to type I primary hyperoxaluria.
Synonyms:Serine-pyruvate aminotransferase, Alanine-glyoxylate aminotransferase, SPT, AGT, AGXT, AGT1, SPAT, PH1, TLH6, AGXT1.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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