The AGTRAP Polyclonal Antibody (CAB12178) is specifically designed for research involving AGTRAP, a protein involved in the regulation of angiotensin II signaling. This antibody, raised in rabbits, is highly reactive with human samples and has been validated for use in various applications, including Western blot and immunoprecipitation.AGTRAP, also known as angiotensin II receptor-associated protein, plays a crucial role in the modulation of angiotensin II receptor signaling, which is involved in regulating blood pressure and vascular function.
Research on AGTRAP is important for understanding its role in hypertension, cardiovascular disease, and other related conditions.By using the AGTRAP Polyclonal Antibody, researchers can effectively detect and analyze AGTRAP protein levels in different cell types, allowing for detailed studies in cardiovascular biology and related fields. This antibody is a valuable tool for investigating the molecular mechanisms underlying angiotensin II signaling and its implications in various disease processes.
Product Name:
AGTRAP Rabbit Polyclonal Antibody
SKU:
CAB12178
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 93-152 of human AGTRAP (NP_065083.3).
This gene encodes a transmembrane protein localized to the plasma membrane and perinuclear vesicular structures. The gene product interacts with the angiotensin II type I receptor and negatively regulates angiotensin II signaling. Alternative splicing of this gene generates multiple transcript variants encoding different isoforms.
Purification Method:
Affinity purification
Gene ID:
57085
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using AGTRAP Rabbit pAb (CAB12178) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
