AGTR1 Rabbit Polyclonal Antibody (CAB14201)
- SKU:
- CAB14201
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | AGTR1 Rabbit Polyclonal Antibody |
SKU: | CAB14201 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 294-388 of human AT1R/AGTR1 (NP_114438.2). |
Sequence: | LIQL GIIR DCRI ADIV DTAM PITI CIAY FNNC LNPL FYGF LGKK FKRY FLQL LKYI PPKA KSHS NLST KMST LSYR PSDN VSSS TKKP APCF EVE |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | AT1; AG2S; AT1B; AT1R; ATR1; AT1AR; AT1BR; AT2R1; HAT1R; AGTR1B; AT1R/AGTR1 |
Positive Sample: | HepG2,U-87MG,C2C12,PC-12 |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Multi-pass membrane protein. |
Calculated MW: | 41kDa |
Observed MW: | 62kDa |
Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. It acts through at least two types of receptors. This gene encodes the type 1 receptor which is thought to mediate the major cardiovascular effects of angiotensin II. This gene may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. It was previously thought that a related gene, denoted as AGTR1B, existed; however, it is now believed that there is only one type 1 receptor gene in humans. Alternative splicing of this gene results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 185 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |