The AGPS Polyclonal Antibody (CAB10484) is an essential tool for researchers studying AGPS, a key enzyme involved in lipid metabolism and cell signaling pathways. This antibody, produced in rabbits, shows high specificity for human samples and has been validated for use in Western blot applications. By binding to the AGPS protein, this antibody enables accurate detection and analysis in a variety of cell types, making it an ideal choice for studies in lipid metabolism, signal transduction, and disease research.AGPS plays a crucial role in the biosynthesis of ether lipid species, which are vital components of cell membranes and are involved in various cellular processes. Dysregulation of AGPS activity has been implicated in a range of diseases, including cancer, neurodegenerative disorders, and metabolic conditions.
Investigating the function of AGPS using this antibody can provide valuable insights into the mechanisms underlying these diseases and facilitate the development of targeted therapies.In summary, the AGPS Polyclonal Antibody (CAB10484) is a valuable tool for researchers seeking to explore the role of AGPS in cellular processes and disease states. Its high reactivity and specificity make it a reliable choice for Western blotting experiments, enabling precise detection and analysis of AGPS protein levels in a variety of research applications.
Product Name:
AGPS Rabbit Polyclonal Antibody
SKU:
CAB10484
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 379-658 of human AGPS (NP_003650.1).
This gene is a member of the FAD-binding oxidoreductase/transferase type 4 family. It encodes a protein that catalyzes the second step of ether lipid biosynthesis in which acyl-dihydroxyacetonephosphate (DHAP) is converted to alkyl-DHAP by the addition of a long chain alcohol and the removal of a long-chain acid anion. The protein is localized to the inner aspect of the peroxisomal membrane and requires FAD as a cofactor. Mutations in this gene have been associated with rhizomelic chondrodysplasia punctata, type 3 and Zellweger syndrome.
Purification Method:
Affinity purification
Gene ID:
8540
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using AGPS Rabbit pAb (CAB10484) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
