The AGPAT9 Polyclonal Antibody (PAC019965) is a valuable tool for researchers studying AGPAT9, an enzyme involved in lipid metabolism. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blotting applications. By binding to the AGPAT9 protein, this antibody allows for the detection and analysis of AGPAT9 expression in various cell types, making it a versatile tool for research in areas such as metabolism, lipid biology, and related diseases.AGPAT9 is known to play a crucial role in the biosynthesis of phospholipids and triglycerides, making it a potential target for the development of therapeutic interventions in metabolic disorders and lipid-related diseases.
By studying the function and regulation of AGPAT9, researchers can gain valuable insights into lipid metabolism and potentially identify novel treatment strategies for conditions such as obesity, diabetes, and cardiovascular disease. The AGPAT9 Polyclonal Antibody is an essential tool for furthering our understanding of AGPAT9 biology and its implications for human health.
Antibody Name:
AGPAT9 Antibody (PACO19965)
Antibody SKU:
PACO19965
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:5000, WB:1:500-1:2000
Species Reactivity:
Human, Mouse
Immunogen:
Synthetic peptide of human AGPAT9
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Gel: 8%SDS-PAGE, Lysate: 80 μg, Lane 1-3: Hela cell and human bladder carcinoma tissue, human normal liver tissue, Primary antibody: PACO19965(AGPAT9 Antibody) at dilution 1/200 dilution, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 15 seconds.
Background:
This gene encodes a member of the lysophosphatidic acid, acyltransferase protein family. The encoded protein is an enzyme which catalyzes the conversion of glycerol-3-phosphate to lysophosphatidic acid, in the synthesis of triacylglycerol. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Synonyms:
1-acylglycerol-3-phosphate O-acyltransferase 9
UniProt Protein Function:
AGPAT9: Esterifies acyl-group from acyl-ACP to the sn-1 position of glycerol-3-phosphate, an essential step in glycerolipid biosynthesis. Overexpression activates the mTOR pathway. Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
UniProt Protein Details:
Protein type:Transferase; Membrane protein, multi-pass; EC 2.3.1.51; EC 2.3.1.15; Membrane protein, integral
Biological Process: phosphatidic acid biosynthetic process; regulation of TOR signaling pathway; triacylglycerol biosynthetic process
NCBI Summary:
This gene encodes a member of the lysophosphatidic acid acyltransferase protein family. The encoded protein is an enzyme which catalyzes the conversion of glycerol-3-phosphate to lysophosphatidic acid in the synthesis of triacylglycerol. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jan 2012]
