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AGPAT9 Antibody (PACO07645)

SKU:
PACO07645
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Applications:
ELISA
WB
IF
Antibody Type:
Polyclonal Antibody
Conjugation:
Unconjugated
€459

Description

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AGPAT9 Antibody (PACO07645)

The AGPAT9 Polyclonal Antibody (PACO7645) is a valuable tool for researchers studying the AGPAT9 protein, a key enzyme involved in lipid metabolism. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By binding specifically to AGPAT9, researchers can detect and analyze this protein in various cell types, providing insights into lipid biosynthesis and its potential role in metabolic disorders and diseases.AGPAT9, also known as 1-acylglycerol-3-phosphate O-acyltransferase 9, is instrumental in the biosynthesis of phosphatidic acid, a crucial precursor for various lipid molecules.

Dysregulation of AGPAT9 has been implicated in metabolic disorders such as obesity, diabetes, and fatty liver disease, making it a promising target for therapeutic intervention. Understanding the function and regulation of AGPAT9 is essential for developing strategies to modulate lipid metabolism and combat related diseases.

Antibody Name:AGPAT9 Antibody (PACO07645)
Antibody SKU:PACO07645
Size:50ul
Host Species:Rabbit
Tested Applications:ELISA, WB, IF
Recommended Dilutions:
Species Reactivity:Human, Mouse, Rat
Immunogen:Human AGPAT9
Form:Liquid
Storage Buffer:PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Purification Method:Antigen Affinity purified
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Synonyms:1-acylglycerol-3-phosphate O-acyltransferase 9;AGPAT9;AGPAT8;GPAT3;HMFN0839;LPAAT-theta;MAG1;MGC11324 ;
UniProt Protein Function:AGPAT9: Esterifies acyl-group from acyl-ACP to the sn-1 position of glycerol-3-phosphate, an essential step in glycerolipid biosynthesis. Overexpression activates the mTOR pathway. Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
UniProt Protein Details:

Protein type:Transferase; Membrane protein, multi-pass; EC 2.3.1.51; EC 2.3.1.15; Membrane protein, integral

Chromosomal Location of Human Ortholog: 4q21.23

Cellular Component: endoplasmic reticulum; endoplasmic reticulum membrane

Molecular Function:1-acylglycerol-3-phosphate O-acyltransferase activity; glycerol-3-phosphate O-acyltransferase activity

Biological Process: phosphatidic acid biosynthetic process; regulation of TOR signaling pathway; triacylglycerol biosynthetic process

NCBI Summary:This gene encodes a member of the lysophosphatidic acid acyltransferase protein family. The encoded protein is an enzyme which catalyzes the conversion of glycerol-3-phosphate to lysophosphatidic acid in the synthesis of triacylglycerol. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jan 2012]
UniProt Code:Q53EU6
NCBI GenInfo Identifier:150403919
NCBI Gene ID:84803
NCBI Accession:Q53EU6.2
UniProt Secondary Accession:Q53EU6,Q68CJ4, Q6GPI6, Q96NA3,
UniProt Related Accession:Q53EU6
Molecular Weight:48,705 Da
NCBI Full Name:Glycerol-3-phosphate acyltransferase 3
NCBI Synonym Full Names:glycerol-3-phosphate acyltransferase 3
NCBI Official Symbol:GPAT3  
NCBI Official Synonym Symbols:MAG1; AGPAT8; AGPAT9; AGPAT10; AGPAT 10; HMFN0839; LPAAT-theta  
NCBI Protein Information:glycerol-3-phosphate acyltransferase 3
UniProt Protein Name:Glycerol-3-phosphate acyltransferase 3
UniProt Synonym Protein Names:1-acyl-sn-glycerol-3-phosphate O-acyltransferase 10; AGPAT 10; 1-acyl-sn-glycerol-3-phosphate O-acyltransferase 9 (EC:2.3.1.51); 1-AGP acyltransferase 9; 1-AGPAT 9; Acyl-CoA:glycerol-3-phosphate acyltransferase 3; hGPAT3; Lung cancer metastasis-associated protein 1; Lysophosphatidic acid acyltransferase theta; LPAAT-theta; MAG-1
UniProt Gene Name:GPAT3  
UniProt Entry Name:GPAT3_HUMAN

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