| UniProt Protein Function: | AGPAT9: Esterifies acyl-group from acyl-ACP to the sn-1 position of glycerol-3-phosphate, an essential step in glycerolipid biosynthesis. Overexpression activates the mTOR pathway. Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. |
| UniProt Protein Details: | Protein type:Transferase; Membrane protein, multi-pass; EC 2.3.1.51; EC 2.3.1.15; Membrane protein, integral Chromosomal Location of Human Ortholog: 4q21.23 Cellular Component: endoplasmic reticulum; endoplasmic reticulum membrane Molecular Function:1-acylglycerol-3-phosphate O-acyltransferase activity; glycerol-3-phosphate O-acyltransferase activity Biological Process: phosphatidic acid biosynthetic process; regulation of TOR signaling pathway; triacylglycerol biosynthetic process |
| NCBI Summary: | This gene encodes a member of the lysophosphatidic acid acyltransferase protein family. The encoded protein is an enzyme which catalyzes the conversion of glycerol-3-phosphate to lysophosphatidic acid in the synthesis of triacylglycerol. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jan 2012] |
| UniProt Code: | Q53EU6 |
| NCBI GenInfo Identifier: | 150403919 |
| NCBI Gene ID: | 84803 |
| NCBI Accession: | Q53EU6.2 |
| UniProt Secondary Accession: | Q53EU6,Q68CJ4, Q6GPI6, Q96NA3, |
| UniProt Related Accession: | Q53EU6 |
| Molecular Weight: | 48,705 Da |
| NCBI Full Name: | Glycerol-3-phosphate acyltransferase 3 |
| NCBI Synonym Full Names: | glycerol-3-phosphate acyltransferase 3 |
| NCBI Official Symbol: | GPAT3Â Â |
| NCBI Official Synonym Symbols: | MAG1; AGPAT8; AGPAT9; AGPAT10; AGPAT 10; HMFN0839; LPAAT-theta  |
| NCBI Protein Information: | glycerol-3-phosphate acyltransferase 3 |
| UniProt Protein Name: | Glycerol-3-phosphate acyltransferase 3 |
| UniProt Synonym Protein Names: | 1-acyl-sn-glycerol-3-phosphate O-acyltransferase 10; AGPAT 10; 1-acyl-sn-glycerol-3-phosphate O-acyltransferase 9 (EC:2.3.1.51); 1-AGP acyltransferase 9; 1-AGPAT 9; Acyl-CoA:glycerol-3-phosphate acyltransferase 3; hGPAT3; Lung cancer metastasis-associated protein 1; Lysophosphatidic acid acyltransferase theta; LPAAT-theta; MAG-1 |
| UniProt Gene Name: | GPAT3Â Â |
| UniProt Entry Name: | GPAT3_HUMAN |
