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AGPAT4 Antibody (PACO15349)

SKU:
PACO15349
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Applications:
ELISA
IHC
Antibody Type:
Polyclonal Antibody
Conjugation:
Unconjugated
  • AGPAT4 Antibody PACO15349
  • AGPAT4 Antibody PACO15349
€339
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Description

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AGPAT4 Antibody (PACO15349)

The AGPAT4 Polyclonal Antibody (PAC015349) is a valuable tool for researchers studying AGPAT4, a key enzyme involved in lipid metabolism and cell membrane biogenesis. This antibody, produced in rabbits, has high reactivity with human samples and is validated for use in Western blot applications. By binding specifically to the AGPAT4 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it an essential component for studies in biochemistry and cell biology.

AGPAT4 plays a crucial role in lipid synthesis and storage, making it an important target for research on metabolic disorders, obesity, and related conditions. Understanding the function of AGPAT4 is essential for developing treatments and interventions that target lipid metabolism pathways. By utilizing the AGPAT4 Polyclonal Antibody, researchers can further elucidate the role of this enzyme in health and disease, paving the way for advancements in personalized medicine and therapeutics.

Antibody Name:AGPAT4 Antibody (PACO15349)
Antibody SKU:PACO15349
Size:50ul
Host Species:Rabbit
Tested Applications:ELISA, IHC
Recommended Dilutions:ELISA:1:2000-1:5000, IHC:1:25-1:100
Species Reactivity:Human, Mouse, Rat
Immunogen:Fusion protein of human AGPAT4
Form:Liquid
Storage Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:Antigen affinity purification
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Product ImageThe image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO15349(AGPAT4 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: x200).
Product ImageThe image on the left is immunohistochemistry of paraffin-embedded Human gastic cancer tissue using PACO15349(AGPAT4 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: x200).
Background:This gene encodes a member of the 1-acylglycerol-3-phosphate O-acyltransferase family. This integral membrane protein converts lysophosphatidic acid, to phosphatidic acid, the second step in de novo phospholipid biosynthesis.
Synonyms:1-acylglycerol-3-phosphate O-acyltransferase 4
UniProt Protein Function:AGPAT4: Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating an acyl moiety at the sn-2 position of the glycerol backbone. Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.Protein type: Transferase; Membrane protein, multi-pass; Membrane protein, integral; Lipid Metabolism - glycerolipid; Lipid Metabolism - ether lipid; EC 2.3.1.51; Lipid Metabolism - glycerophospholipidChromosomal Location of Human Ortholog: 6q26Cellular Component: endoplasmic reticulum membraneMolecular Function: 1-acylglycerol-3-phosphate O-acyltransferase activity; protein bindingBiological Process: phosphatidic acid biosynthetic process; triacylglycerol biosynthetic process
UniProt Protein Details:
NCBI Summary:This gene encodes a member of the 1-acylglycerol-3-phosphate O-acyltransferase family. This integral membrane protein converts lysophosphatidic acid to phosphatidic acid, the second step in de novo phospholipid biosynthesis. [provided by RefSeq, Jul 2008]
UniProt Code:Q9NRZ5
NCBI GenInfo Identifier:12230468
NCBI Gene ID:56895
NCBI Accession:Q9NRZ5.1
UniProt Secondary Accession:Q9NRZ5,Q5TEF0, B4DSF9
UniProt Related Accession:Q9NRZ5
Molecular Weight:24,951 Da
NCBI Full Name:1-acyl-sn-glycerol-3-phosphate acyltransferase delta
NCBI Synonym Full Names:1-acylglycerol-3-phosphate O-acyltransferase 4
NCBI Official Symbol:AGPAT4  
NCBI Official Synonym Symbols:1-AGPAT4; dJ473J16.2; LPAAT-delta  
NCBI Protein Information:1-acyl-sn-glycerol-3-phosphate acyltransferase delta
UniProt Protein Name:1-acyl-sn-glycerol-3-phosphate acyltransferase delta
UniProt Synonym Protein Names:1-acylglycerol-3-phosphate O-acyltransferase 4; 1-AGP acyltransferase 4; 1-AGPAT 4; Lysophosphatidic acid acyltransferase delta; LPAAT-delta
Protein Family:1-acyl-sn-glycerol-3-phosphate acyltransferase
UniProt Gene Name:AGPAT4  
UniProt Entry Name:PLCD_HUMAN
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