The AGPAT1 Polyclonal Antibody (CAB6517) is a valuable tool for researchers studying AGPAT1, an enzyme involved in lipid metabolism. This antibody, produced in rabbits, has high reactivity with human samples and has been validated for Western blot applications. It specifically binds to the AGPAT1 protein, allowing for precise detection and analysis in a variety of cell types.AGPAT1 is a key player in the biosynthesis of glycerophospholipids and triglycerides, making it a crucial target for research related to metabolic disorders, obesity, and insulin resistance.
By understanding the function and regulation of AGPAT1, researchers can gain insight into the underlying mechanisms of these conditions and develop potential therapeutic strategies.Overall, the AGPAT1 Polyclonal Antibody is a reliable tool for investigating the role of AGPAT1 in lipid metabolism and its implications in various diseases, providing valuable information for advancing research in the field of biochemistry and molecular biology.
Product Name:
AGPAT1 Rabbit Polyclonal Antibody
SKU:
CAB6517
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 204-283 of human AGPAT1 (NP_006402.1).
This gene encodes an enzyme that converts lysophosphatidic acid (LPA) into phosphatidic acid (PA). LPA and PA are two phospholipids involved in signal transduction and in lipid biosynthesis in cells. This enzyme localizes to the endoplasmic reticulum. This gene is located in the class III region of the human major histocompatibility complex. Alternative splicing results in two transcript variants encoding the same protein.
Purification Method:
Affinity purification
Gene ID:
10554
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using AGPAT1 Rabbit pAb (CAB6517) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
