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AGO4 Antibody

SKU:
PACO64589
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Applications:
ELISA
IF
Conjugation:
Unconjugated
Isotype:
IgG
Host Species:
Rabbit
$383
Frequently bought together:

Description

AGO4 Antibody (PACO64589)

The AGO4 polyclonal antibody (PAC064589) is a powerful tool for researchers studying AGO4, a key player in gene silencing mediated by small RNAs. This antibody, generated in rabbits, exhibits high specificity and sensitivity in detecting AGO4 in a variety of samples, particularly human tissues. Validated for use in Western blot applications, it allows for precise analysis of AGO4 expression levels in different cell types.AGO4 is a crucial component of the RNA-induced silencing complex (RISC), which is responsible for mediating post-transcriptional gene silencing. By targeting specific mRNA molecules for degradation or translational repression, AGO4 plays a central role in regulating gene expression and maintaining genome stability.

Its involvement in RNA interference pathways makes it a focal point for research in molecular biology and genetics.Studying the function of AGO4 is essential for unraveling the mechanisms underlying gene regulation, development, and disease. The AGO4 polyclonal antibody provides a reliable tool for investigating the role of AGO4 in various biological processes and understanding its implications in cancer, neurodegenerative disorders, and other pathological conditions. Unlock the potential of AGO4 research with this high-quality antibody.

Product Name:AGO4 Antibody
Product Code:PACO64589
Size:50µL
Target Names:AGO4
Species Reactivity:Human
Host Species:Rabbit
Antigen Species:Human
Tested Applications:ELISA, IF; Recommended dilution: IF:1:100-1:500
Isotype:IgG
Clone ID:N/A
Conjugate:Non-conjugated
Clonality:Polyclonal
Antigen:Recombinant Human Protein argonaute-4 protein (716-861aa)
Form:Liquid
Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method:>95%, Protein G purified
Storage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Aliases:Protein argonaute-4 (Argonaute4) (hAgo4) (Argonaute RISC catalytic component 4) (Eukaryotic translation initiation factor 2C 4) (eIF-2C 4) (eIF2C 4), AGO4, EIF2C4 KIAA1567
Uniprot ID:Q9HCK5
Background:Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. Also required for RNA-directed transcription and replication of the human hapatitis delta virus (HDV).
Research Area:Neuroscience

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