The AGFG2 Polyclonal Antibody (PACO04074) is a valuable tool for researchers studying AGFG2, a protein involved in intracellular trafficking and membrane fusion processes. This antibody, raised in rabbits, is highly specific for AGFG2 in human samples and is validated for use in various applications, including Western blot and immunohistochemistry.AGFG2, also known as Arf-GAP domain and FG repeat-containing protein 2, is essential for the proper functioning of cellular pathways involved in vesicle transport and secretion. Its role in regulating vesicle trafficking makes it a key target for studies in cell biology and neurobiology.
The AGFG2 Polyclonal Antibody enables researchers to detect and analyze AGFG2 expression in different cell types, providing valuable insights into its function and localization within cells.Understanding the function of AGFG2 is critical for unraveling its involvement in diseases such as neurodegenerative disorders and cancer, where aberrant vesicle trafficking processes can contribute to pathogenesis. By using the AGFG2 Polyclonal Antibody in their research, scientists can elucidate the specific roles of AGFG2 in cellular processes and potentially identify new therapeutic targets for these conditions.
Antibody Name:
AGFG2 Antibody
Antibody SKU:
PACO04074
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
WB:1:500-1:2000
Species Reactivity:
Human, Mouse
Immunogen:
synthesized peptide derived from the Internal region of human Rabr.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
AGFG2; HRBL; RABR; Arf-GAP domain and FG repeat-containing protein 2; HIV-1 Rev-binding protein-like protein; Rev/Rex activation domain-binding protein related; RAB-R
UniProt Protein Function:
HRBL: 2 isoforms of the human protein are produced by alternative splicing.Protein type: Unknown functionChromosomal Location of Human Ortholog: 7q22.1Cellular Component: membrane
UniProt Protein Details:
NCBI Summary:
This gene is a member of the HIV-1 Rev binding protein (HRB) family and encodes a protein with one Arf-GAP zinc finger domain, several phe-gly (FG) motifs, and four asn-pro-phe (NPF) motifs. This protein interacts with Eps15 homology (EH) domains and plays a role in the Rev export pathway, which mediates the nucleocytoplasmic transfer of proteins and RNAs. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Feb 2013]
