The AGFG1 Polyclonal Antibody (CAB13500) is a valuable tool for research involving the AGFG1 protein, a key regulator of intracellular trafficking and signaling pathways. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By specifically binding to the AGFG1 protein, this antibody enables precise detection and analysis in a variety of cell types, making it an essential component for studies in cell biology and signal transduction research.AGFG1, also known as Arf-GAP domain and FG repeats-containing protein 1, is involved in the transport of proteins between cellular compartments and the regulation of signal transduction pathways.
Its role in maintaining proper cellular function makes it a crucial target for research into various diseases, including cancer, neurodegenerative disorders, and infectious diseases. By studying the function of AGFG1, researchers can gain insights into the mechanisms underlying these diseases and potentially develop targeted therapies to disrupt or enhance its activity for therapeutic benefit.
Product Name:
AGFG1 Rabbit Polyclonal Antibody
SKU:
CAB13500
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human AGFG1 (NP_004495.2).
The protein encoded by this gene is related to nucleoporins, a class of proteins that mediate nucleocytoplasmic transport. The encoded protein binds the activation domain of the human immunodeficiency virus Rev protein when Rev is assembled onto its RNA target, and is required for the nuclear export of Rev-directed RNAs. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
3267
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using AGFG1 antibody (CAB13500) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 30s.
